Molecular microbiology techniques form the backbone of our research, with tools such as genomics, transcriptomics, and metagenomics employed to dissect pathogen behaviour at the genetic and biochemical levels. These omics technologies allow us to examine the gene expression profiles, metabolic pathways, and host interactions that are central to pathogen survival and virulence. For example, our studies of the unfolded protein response (UPR) in human intestinal epithelial cells (IECs) provide insight into how Campylobacter manipulates host cell stress responses to promote persistence in the gut.

We also apply bioinformatics to identify and functionally analyse virulence factors like the Type VI Secretion System (T6SS), which mediates bacterial antagonism and host manipulation. Our research on outer membrane vesicles (OMVs) and their role in pathogen-host interactions further contributes to our understanding of how bacteria communicate with and subvert host defences.

By integrating these cutting-edge techniques with traditional microbiology approaches, we aim to develop a comprehensive understanding of the molecular processes that drive bacterial pathogenesis. These insights provide a foundation for identifying novel targets for therapeutic intervention, offering the potential to reduce the public health burden of foodborne diseases.